We have participated in Cancer Research Trials since June of 1986. We have entered over 500 patients in clinical trials. These trials lead to new FDA approvals, for chemotherapeutic agents, immunotherapy and targeted therapy drugs.
As a person who has been diagnosed with cancer, you should be well informed. You may have several treatment choices. It is important to learn about your options. One choice you may have is a cancer clinical trial. If you are interested in participating in a clinical trial, consult with your physician. Please note: clinical trials are not risk-free. Patients must explore the options that are best for their individual needs with the help of their physician.
Trials we participate in are Phase II and Phase III, no Phase 1. Examples of trials we have participated in are: Brain, Breast, Carcinoid, Colon, Gastric, Head and Neck, Leukemia, Lung, Lymphoma, Melanoma, Myeloma, Ovarian, Prostate, Rectal, Renal, Sarcoma, and Prostate Prevention. We also participate in Biospecimen protocols, registries, and quality of life studies.
million cancer survivors in the U.S. are living with, through, and beyond their disease thanks to research.
cancer diagnoses in the United States are associated with preventable risk factors.
million people are projected to be diagnosed with cancer worldwide by the year 2040
new therapeutics against cancer were approved by the FDA from 2021 to 2022.
They are the final step in a long process that begins with research in a lab. Many treatments used today are the result of past clinical trials.In cancer research, clinical trials are designed to answer questions about new ways to:
• Treat Cancer
• Find and diagnose cancer
• Prevent cancer
• Manage symptoms of cancer or its treatment
Clinical trials take place in phases. For a treatment to become part of standard treatment, it must first go through 3 or 4 clinical trial phases. You do not have to take part in all phases. The early phases make sure the treatment is safe. Later phases show if it works better than the standard treatment.
The Cancer Centers of Southwest Oklahoma only participates in Phase II and III clinical trials.
Phase I trials find safe doses, to decide how the new treatment should be given and to see how the new treatment affects the human body. Usually 13-30 people take part in a study of this nature.
Phase II trials determine if the new treatment has an effect on a certain cancer and evaluates how the new treatment affects the human body. Usually less than 100 people take part in these studies.
Phase III trials compare the new treatment (or new use of a treatment) with the current standard treatment. These trials enroll from 100 to thousands of people.
Phase I trials find safe doses, to decide how the new treatment should be given and to see how the new treatment affects the human body. Usually 13-30 people take part in a study of this nature.
Phase II trials determine if the new treatment has an effect on a certain cancer and evaluates how the new treatment affects the human body. Usually less than 100 people take part in these studies.
Phase III trials compare the new treatment (or new use of a treatment) with the current standard treatment. These trials enroll from 100 to thousands of people.
If a new treatment is proven to work and you are taking it, you may be among the first to benefit. You have the chance to help others and improve cancer treatment.
The possible benefits of participating in a Cancer clinical trial are:
• We will watch you very closely – perhaps even more closely than if you were not in a trial.
• You may be the first to benefit from the new treatment if it is found to be helpful.
• You have the chance to make a valuable contribution to cancer research.
• The standard treatments available today are the result of people participating in clinical trials.
The possible risks of participating in a Cancer clinical trial are:• All treatments may have side effects and/or risks.
• The new treatment may not be as effective as standard care or may not be effective at all.
• The new treatment may not work for you even if it has worked on others.
• There may be costs that are not covered by insurance or the trial sponsor.
Absolutely. One of your key rights in a clinical trial is the right to informed consent. You must be given all of the known facts about a study before you make a decision to participate. Then you will know about the possible benefits, known risks and or side effects that may affect you. You also have the right to opt out of a study at any time.
It can easily be overwhelming: the diagnosis, the information, the choices. If you feel overwhelmed about the amount or type of information you are given, ask to talk with an oncology Nurse Navigator. You may learn that the choices are not as intimidating as they seem.
No. You will receive either the new treatment or the best standard treatment available. People who received treatment through a clinical trial generally find it to be a very positive experience and feel that they received good care and attention, no matter what the outcome of the disease.
Schedule a meeting to talk with your oncologist about clinical trials. Bring a list of questions and a family member or friend to help. You may also wish to seek a second opinion at an NCI cancer center where they specialize in clinical trials. You should be open to options throughout the course of your treatment because it’s never too late to access the best care available to you.
Randomization is a process used in some clinical trials to prevent bias. Bias occurs when a trial’s results are affected by human choices or other factors not related to the treatment being tested.
No. Some clinical trials can be considered before you start any other treatment, at any time throughout treatment, or at time of recurrence, depending on available studies. Cancer clinical trials come in many forms and test many aspects of cancer care, including ways to reduce infection or pain, nausea, or other side effects, as well as ways to potentially cure the cancer.
A placebo is designed to look like the medicine being tested, but it is not active. In some cases, a study may compare standard treatment plus a new treatment, to standard treatment plus a placebo. You will be told if the study uses a placebo.
Clinical trials offer high-quality cancer care. If you are in a randomized study and do not receive the new treatment being tested, you will receive the best- known standard treatment. This may be as good as, or better than, the new approach.
If a new treatment is proven to work and you are taking it, you may be among the first to benefit. You have the chance to help others and improve cancer treatment.
To download PDF of Clinical Trials Information, CLICK HERE.